Bacterial and Fungal Co-Infections among ICU COVID-19 Hospitalized Patients in a Palestinian Hospital: Incidence and Antimicrobial Stewardship (preprint)

Diagnosis of co-infections with multiple pathogens among hospitalized COVID-19 patients can be jointly challenging and very essential for appropriate treatment, shortening hospital stay and preventing antimicrobial resistance. This study proposes to investigate the burden of bacterial and fungal co-infections outcomes on COVID-19 patients. It is a single centre cross-sectional study of hospitalized COVID-19 patients at Beit-Jala hospital in Palestine. The study included 321 hospitalized patients admitted to the ICU between June 2020 and March 2021 aged [≥] 20 years, with a confirmed diagnosis of COVID-19 via RT-PCR conducted on a nasopharyngeal swab. The patients information was gathered using graded data forms from electronic medical reports. The diagnosis of bacterial and fungal infection was proved through the patients clinical presentation and positive blood or sputum culture results. All cases had received empirical antimicrobial therapy before the ICU admission, and different regimens during the ICU stay. The rate of bacterial co-infection was 51.1%, mainly from gram-negative isolates (Enterobacter species and K.pneumoniae). The rate of fungal co-infection caused by A.fumigatus was 48.9%, and the mortality rate was 8.1%. However, it is unclear if it had been attributed to SARS-CoV-2 or coincidental.

Impact of COVID-19 Pandemic on the Psychological Status of Palestinian Adults in the West Bank, Palestine; A Cross Sectional Study (preprint)

Coronavirus Disease 2019 (COVID-19) caused by a strain of SARS– CoV2. A lot of ministries chose mass lockdown protocol as a way to control the virus spread. One of the lockdown negative consequences is the impact of psychological status which includes a sense of boredom, confusion., psychological stress, anxiety, depression and physical effects. The purpose of this study was to assess and evaluate the effect of COVID-19 pandemic on the psychological status for Palestinian adults, and to establish recommendations in order to promote and maintain psychological well-being during this pandemic. A cross-sectional study was conducted among Palestinian adults, 739 participant with mean age 31.76 filled the on-line questionnaire. Around one-third of respondents revealed having many signs of anxiety and around 42% of respondents expressed having many depression signs. Females were significantly more likely to have many depression signs, while health care workers, those who deal directly with confirmed cases of Covid-19 and who assist in providing health care for a diagnosed Covid-19 patient were significantly less likely to have many depression signs compared to others. Regarding the participants’ income, those with increased income were significantly more likely to have almost no signs of depression compared to others. However, COVID-19 pandemic has a negative effect on the mental status, the majority of participants have signs of anxiety and depression